/* ==========================================================================
   Item 108 · 343 — Confusion mentale, démence et état confusionnel
   Palette principale : --spe-neuro (aubergine), accents --warn / --ok / --danger.
   ========================================================================== */

:root {
  --paper:    var(--bg-card);
  --paper-2:  #fffcf5;
  --rule:     #d7ccb4;
  --rule-2:   var(--accent-dash);
  --bg-2:     #ece5d6;
  --bg-3:     #e4dcc8;
  --ink-2:    #524a3e;
  --ink-3:    #8a8270;
  --ink-4:    #b2a98f;
  --danger:   #a52a1a;
  --warn:     #8a5a12;
  --ok:       #4e6a2f;

  /* Familles thématiques pour la mindmap */
  --fam-def:      var(--spe-neuro);
  --fam-physio:   var(--spe-cardio);
  --fam-etio:     var(--spe-infectio);
  --fam-paraclin: var(--spe-orl);
  --fam-dd:       var(--warn);
  --fam-pec:      var(--ok);
}

/* Élargissement de la zone de contenu */
.content { max-width: 1400px; }

/* Fade léger au changement d'onglet */
@keyframes ced-fadeIn {
  from { opacity: 0; transform: translateY(6px); }
  to   { opacity: 1; transform: none; }
}
.content-panel.active { animation: ced-fadeIn .35s ease-out; }

/* Utilitaires */
.mono   { font-family: var(--font-mono); font-feature-settings: "ss01"; }
.muted  { color: var(--ink-3); }

/* =========================================================
   Sec-title
   ========================================================= */
.sec-title       { display: flex; align-items: baseline; gap: 16px; margin: 36px 0 18px; flex-wrap: wrap; }
.sec-num         { font-family: var(--font-mono); font-size: 11px; letter-spacing: .18em; color: var(--ink-3); text-transform: uppercase; }
.sec-title h2    { font-family: var(--font-serif); font-weight: 500; font-size: 30px; letter-spacing: -.01em; margin: 0; line-height: 1; }
.sec-title .rule { flex: 1; height: 1px; background: var(--rule); margin-bottom: 8px; min-width: 40px; }
.sec-title .hint { font-family: var(--font-mono); font-size: 11px; color: var(--ink-3); letter-spacing: .06em; }

.rang-tag {
  display: inline-flex; align-items: center; gap: 5px;
  font-family: var(--font-mono); font-size: 10px; letter-spacing: .14em; text-transform: uppercase;
  padding: 3px 8px; border-radius: 2px;
  border: 1px solid var(--rule-2); color: var(--ink-2); background: var(--paper);
  vertical-align: middle;
}
.rang-tag.rang-a  { color: var(--ok);    border-color: color-mix(in oklab, var(--ok) 40%, var(--rule-2)); }
.rang-tag.rang-b  { color: var(--ink-3); border-color: var(--rule-2); }
.rang-tag.rang-ab { color: var(--warn);  border-color: color-mix(in oklab, var(--warn) 40%, var(--rule-2)); }

/* =========================================================
   Cat-block & Hbox
   ========================================================= */
.cat-block {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--spe-neuro); border-radius: 3px;
  padding: 12px 16px; margin-bottom: 12px;
}
.cat-block .cat-label {
  font-family: var(--font-mono); font-size: 10px; letter-spacing: .14em; text-transform: uppercase;
  color: var(--spe-neuro); margin-bottom: 6px; font-weight: 500;
}
.cat-block ul    { margin: 4px 0 0; padding-left: 18px; font-size: 13px; color: var(--ink-2); }
.cat-block ul li { margin: 5px 0; line-height: 1.5; }
.cat-block.cat-protect { border-left-color: var(--ok); }
.cat-block.cat-protect .cat-label { color: var(--ok); }
.cat-block p     { margin: 4px 0; font-size: 13px; color: var(--ink-2); }

.hstack { display: flex; flex-direction: column; gap: 10px; }
.hbox {
  background: var(--paper); border: 1px solid var(--rule); border-radius: 3px;
  padding: 12px 16px;
  display: grid; grid-template-columns: 88px 1fr; gap: 4px 16px; align-items: baseline;
}
.hbox > .n {
  grid-column: 1; grid-row: 1 / -1;
  align-self: start; padding-top: 2px;
  font-family: var(--font-mono); font-size: 10.5px;
  letter-spacing: .08em; color: var(--spe-neuro); font-weight: 500;
  word-break: break-word; line-height: 1.3; text-transform: uppercase;
}
.hbox > h5      { grid-column: 2; font-family: var(--font-serif); font-weight: 500; font-size: 15px; margin: 0 0 4px; }
.hbox > p,
.hbox > ul      { grid-column: 2; margin: 0; font-size: 13px; color: var(--ink-2); line-height: 1.6; }
.hbox > ul      { padding-left: 18px; }
.hbox > ul li   { margin: 5px 0; }
.hbox + .hbox   { margin-top: 10px; }

/* =========================================================
   Tables (.matrix)
   ========================================================= */
table.matrix              { width: 100%; border-collapse: collapse; background: var(--paper); border: 1px solid var(--rule); margin-bottom: 16px; }
table.matrix th,
table.matrix td           { padding: 11px 13px; text-align: left; border-bottom: 1px solid var(--rule); vertical-align: top; font-size: 13px; line-height: 1.5; }
table.matrix thead th     { background: var(--bg-2); font-family: var(--font-mono); font-size: 10px; letter-spacing: .14em; text-transform: uppercase; color: var(--ink-2); font-weight: 500; border-bottom: 1px solid var(--rule-2); }
table.matrix tbody th     { font-family: var(--font-serif); font-weight: 500; font-size: 14.5px; color: var(--ink); border-right: 1px solid var(--rule); width: 22%; }
table.matrix tbody tr:last-child th,
table.matrix tbody tr:last-child td { border-bottom: none; }
table.matrix tbody tr:hover td      { background: var(--paper-2); }
table.matrix ul           { margin: 0; padding-left: 18px; }
table.matrix ul li        { margin: 4px 0; }

.th-sub { display: block; font-family: var(--font-mono); font-size: 9px; letter-spacing: .08em; color: var(--ink-3); font-weight: 400; margin-top: 2px; text-transform: none; }

/* =========================================================
   Vignette + keypoints + définitions (onglet 03)
   ========================================================= */
.vignette {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 4px solid var(--spe-neuro); border-radius: 4px;
  padding: 20px 24px; margin-bottom: 24px;
}
.vignette .vg-tag {
  font-family: var(--font-mono); font-size: 10px; letter-spacing: .18em; text-transform: uppercase;
  color: var(--spe-neuro); margin-bottom: 8px;
}
.vignette p {
  font-family: var(--font-serif); font-size: 15px; line-height: 1.55; color: var(--ink); margin: 0;
}
.vignette .vg-trap {
  margin-top: 14px; padding: 12px 16px;
  background: var(--bg-2); border-radius: 3px;
  font-family: var(--font-sans); font-size: 13px; color: var(--ink-2); line-height: 1.5;
}

.kp-grid {
  display: grid; grid-template-columns: repeat(2, 1fr); gap: 14px; margin-bottom: 24px;
}
.kp-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--spe-neuro); border-radius: 3px;
  padding: 14px 18px;
  display: grid; grid-template-columns: 40px 1fr; gap: 10px; align-items: start;
}
.kp-card .kp-num {
  font-family: var(--font-mono); font-size: 18px; font-weight: 600;
  color: var(--spe-neuro); letter-spacing: .04em;
}
.kp-card p { margin: 0; font-size: 13px; line-height: 1.55; color: var(--ink-2); }

.def-grid { display: grid; grid-template-columns: repeat(2, 1fr); gap: 14px; }
.def-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-top: 4px solid var(--spe-neuro); border-radius: 4px;
  padding: 16px 18px;
}
.def-card .def-head { display: flex; align-items: baseline; gap: 10px; margin-bottom: 8px; flex-wrap: wrap; }
.def-card h3 { font-family: var(--font-serif); font-weight: 500; font-size: 19px; letter-spacing: -.01em; margin: 0; color: var(--spe-neuro); }
.def-card .def-sub { font-family: var(--font-mono); font-size: 10.5px; letter-spacing: .08em; text-transform: uppercase; color: var(--ink-3); }
.def-card p { margin: 0; font-size: 12.5px; color: var(--ink-2); line-height: 1.5; }

/* Formes cliniques — table */
.formes-tab tr.forme-hyper { background: color-mix(in oklab, var(--spe-infectio) 4%, transparent); }
.formes-tab tr.forme-hypo  { background: color-mix(in oklab, var(--warn) 8%, transparent); }
.formes-tab tr.forme-mixte { background: color-mix(in oklab, var(--spe-neuro) 4%, transparent); }
.formes-tab tr.forme-hypo th { color: var(--warn); }

/* DSM-5 cards (A → E) */
.dsm-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(260px, 1fr)); gap: 12px; margin-bottom: 16px; }
.dsm-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--spe-cardio); border-radius: 3px;
  padding: 14px 16px;
}
.dsm-card .dsm-head { display: flex; align-items: baseline; gap: 12px; margin-bottom: 8px; }
.dsm-card .dsm-letter {
  font-family: var(--font-serif); font-size: 28px; font-weight: 500;
  color: var(--spe-cardio); line-height: 1;
}
.dsm-card h4 { font-family: var(--font-serif); font-weight: 500; font-size: 15px; margin: 0; color: var(--ink); }
.dsm-card p  { margin: 0; font-size: 12.5px; color: var(--ink-2); line-height: 1.55; }

/* Bloc CAM */
.cam-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-top: 4px solid var(--ok); border-radius: 4px;
  padding: 18px 22px; margin-bottom: 18px;
}
.cam-card .cam-formule {
  font-family: var(--font-serif); font-size: 18px; color: var(--ok);
  margin-bottom: 12px; text-align: center;
}
.cam-list { padding-left: 22px; margin: 8px 0; font-size: 13px; color: var(--ink-2); }
.cam-list li { margin: 5px 0; line-height: 1.5; }
.cam-foot {
  font-family: var(--font-mono); font-size: 11px; letter-spacing: .08em;
  color: var(--ink-3); text-align: center; margin-top: 10px;
}
.cam-schema { margin-top: 14px; border-left-color: var(--ok); }
.cam-schema .cam-box      { fill: var(--paper-2); stroke: var(--ok); stroke-width: 1.2; }
.cam-schema .cam-box.req  { stroke: var(--ok); }
.cam-schema .cam-box.alt  { stroke: var(--warn); fill: color-mix(in oklab, var(--warn) 6%, var(--paper-2)); }
.cam-schema .cam-box.result { fill: var(--ok); stroke: var(--ok); }
.cam-schema .cam-box.result + text,
.cam-schema .cam-box.result ~ text { fill: var(--paper); }
.cam-schema .cam-label-num { font-family: var(--font-mono); font-size: 11px; fill: var(--ok); font-weight: 600; letter-spacing: .08em; }
.cam-schema .cam-box.result ~ .cam-label-num { fill: var(--paper); }
.cam-schema .cam-label    { font-family: var(--font-sans); font-size: 11px; fill: var(--ink-2); }
.cam-schema .cam-op       { font-family: var(--font-mono); font-size: 11px; fill: var(--ink-3); font-weight: 600; letter-spacing: .08em; }
.cam-schema .cam-arrow    { stroke: var(--ok); stroke-width: 2; fill: none; marker-end: url(#arrowOk); }

/* =========================================================
   Mindmap radiale
   ========================================================= */
.mmwrap {
  position: relative; background: var(--paper); border: 1px solid var(--rule);
  border-radius: 4px; overflow: hidden; height: 760px;
}
.mmwrap .zctl        { position: absolute; top: 14px; right: 14px; z-index: 10; display: flex; gap: 4px; }
.mmwrap .zctl button {
  width: 34px; height: 34px; border: 1px solid var(--rule-2); background: var(--paper);
  border-radius: 3px; font-family: var(--font-mono); font-size: 14px; color: var(--ink-2);
  cursor: pointer;
}
.mmwrap .zctl button:hover { background: var(--bg-2); }
.mmwrap .zhint {
  position: absolute; left: 14px; bottom: 14px; z-index: 10;
  font-family: var(--font-mono); font-size: 10px; letter-spacing: .08em;
  color: var(--ink-3); background: rgba(255, 252, 245, .85);
  padding: 6px 10px; border-radius: 3px; border: 1px solid var(--rule);
}
.mmwrap svg.canvas {
  width: 100%; height: 100%; display: block; cursor: grab;
  background-image: radial-gradient(circle at 1px 1px, rgba(0,0,0,.035) 1px, transparent 0);
  background-size: 24px 24px;
}
.mmwrap svg.canvas:active { cursor: grabbing; }
.mmwrap svg.canvas .root-circle  { fill: var(--spe-neuro); }
.mmwrap svg.canvas .root-text    { fill: var(--paper); font-family: var(--font-serif); font-weight: 500; }
.mmwrap svg.canvas .node-card    { cursor: pointer; }
.mmwrap svg.canvas .node-card:hover .node-bg { stroke-width: 2; }
.mmwrap svg.canvas .node-bg      { fill: #fff; stroke: var(--rule-2); stroke-width: 1; }
.mmwrap svg.canvas .node-accent  { fill: var(--spe-neuro); }
.mmwrap svg.canvas .node-card.fam-def      .node-accent { fill: var(--fam-def); }
.mmwrap svg.canvas .node-card.fam-physio   .node-accent { fill: var(--fam-physio); }
.mmwrap svg.canvas .node-card.fam-etio     .node-accent { fill: var(--fam-etio); }
.mmwrap svg.canvas .node-card.fam-paraclin .node-accent { fill: var(--fam-paraclin); }
.mmwrap svg.canvas .node-card.fam-dd       .node-accent { fill: var(--fam-dd); }
.mmwrap svg.canvas .node-card.fam-pec      .node-accent { fill: var(--fam-pec); }
.mmwrap svg.canvas .node-title   { fill: var(--ink); font-family: var(--font-serif); font-weight: 500; font-size: 15px; }
.mmwrap svg.canvas .node-sub     { fill: var(--ink-2); font-size: 11px; }
.mmwrap svg.canvas .node-chip    { fill: #fff; stroke: var(--rule); stroke-width: 1; }
.mmwrap svg.canvas .node-chip-t  { fill: var(--ink-2); font-family: var(--font-mono); font-size: 9px; letter-spacing: .08em; text-transform: uppercase; }
.mmwrap svg.canvas path.link     { fill: none; stroke: var(--rule-2); stroke-width: 1.2; stroke-dasharray: 3 4; }
.mmwrap svg.canvas path.link.main   { stroke-width: 1.4; }
.mmwrap svg.canvas path.link.sat    { stroke: var(--rule-2); stroke-width: 1; stroke-dasharray: 1 5; opacity: .55; }
.mmwrap svg.canvas .ring         { fill: none; stroke: var(--rule); stroke-width: 1; stroke-dasharray: 2 5; }

.mmwrap svg.canvas .node-sat                 { cursor: pointer; }
.mmwrap svg.canvas .node-sat:hover .sat-bg   { fill: var(--spe-neuro); }
.mmwrap svg.canvas .node-sat:hover .sat-title,
.mmwrap svg.canvas .node-sat:hover .sat-sub  { fill: var(--paper); }
.mmwrap svg.canvas .sat-bg                   { fill: var(--bg-2); stroke: var(--spe-neuro); stroke-width: 1; }
.mmwrap svg.canvas .sat-title                { fill: var(--ink); font-family: var(--font-serif); font-weight: 500; font-size: 12.5px; }
.mmwrap svg.canvas .sat-sub                  { fill: var(--ink-2); font-size: 9.5px; font-family: var(--font-mono); letter-spacing: .04em; }

/* =========================================================
   Alerte rouge
   ========================================================= */
.alert-card {
  background: #f3dccf;
  border: 1px solid var(--danger);
  border-left: 4px solid var(--danger);
  border-radius: 3px;
  padding: 16px 20px;
  margin: 18px 0;
}
.alert-card .alert-head { display: flex; align-items: baseline; gap: 12px; flex-wrap: wrap; margin-bottom: 10px; }
.alert-card .alert-tag {
  font-family: var(--font-mono); font-size: 10px; letter-spacing: .14em; text-transform: uppercase;
  color: var(--danger); padding: 3px 8px; border: 1px solid var(--danger);
  border-radius: 2px; background: var(--paper);
}
.alert-card h3 { font-family: var(--font-serif); font-weight: 500; font-size: 18px; margin: 0; color: var(--ink); }
.alert-card p  { margin: 6px 0; font-size: 13px; color: var(--ink-2); line-height: 1.55; }
.alert-card ul { margin: 6px 0; padding-left: 20px; font-size: 13px; color: var(--ink-2); }
.alert-card ul li { margin: 5px 0; line-height: 1.5; }

/* =========================================================
   Tableau pivot Confusion vs Démence (onglet 05)
   ========================================================= */
.conf-dem-tab thead th.col-conf { background: color-mix(in oklab, var(--warn) 16%, var(--bg-2)); color: var(--warn); }
.conf-dem-tab thead th.col-dem  { background: color-mix(in oklab, var(--spe-neuro) 14%, var(--bg-2)); color: var(--spe-neuro); }
.conf-dem-tab .cell-conf        { background: color-mix(in oklab, var(--warn) 5%, transparent); }
.conf-dem-tab .cell-dem         { background: color-mix(in oklab, var(--spe-neuro) 5%, transparent); }
.conf-dem-tab tr.row-key th     { background: var(--bg-3); }

/* 3 cards DD complémentaires */
.dd-cards-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr)); gap: 14px; margin-bottom: 16px; }
.dd-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--warn); border-radius: 3px;
  padding: 14px 16px;
}
.dd-card .dd-head { display: flex; align-items: baseline; gap: 10px; margin-bottom: 8px; padding-bottom: 8px; border-bottom: 1px dashed var(--rule); }
.dd-card .dd-icon { font-size: 22px; line-height: 1; }
.dd-card h4 { font-family: var(--font-serif); font-weight: 500; font-size: 16px; margin: 0; color: var(--ink); }
.dd-line {
  margin: 5px 0; font-size: 12.5px; color: var(--ink-2); line-height: 1.5;
}
.dd-line b {
  display: inline-block; min-width: 92px;
  font-family: var(--font-mono); font-size: 9.5px; letter-spacing: .08em; text-transform: uppercase;
  color: var(--ink-3); font-weight: 500; vertical-align: top;
}

/* =========================================================
   Etiologies (onglet 06)
   ========================================================= */
.etio-grid {
  display: grid; grid-template-columns: repeat(auto-fit, minmax(260px, 1fr));
  gap: 14px; margin-bottom: 16px;
}
.etio-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-top: 4px solid var(--spe-neuro); border-radius: 4px;
  padding: 14px 18px;
}
.etio-card.etio-tox    { border-top-color: var(--danger); }
.etio-card.etio-meta   { border-top-color: var(--spe-cardio); }
.etio-card.etio-neuro  { border-top-color: var(--spe-neuro); }
.etio-card.etio-autres { border-top-color: var(--spe-infectio); }
.etio-card .etio-head  { display: flex; align-items: baseline; gap: 10px; margin-bottom: 8px; }
.etio-card .etio-icon  { font-size: 22px; line-height: 1; }
.etio-card h4          { font-family: var(--font-serif); font-weight: 500; font-size: 17px; margin: 0; color: var(--ink); }
.etio-card ul          { margin: 4px 0 0; padding-left: 18px; font-size: 12.5px; color: var(--ink-2); }
.etio-card ul li       { margin: 5px 0; line-height: 1.5; }

/* Carences vitaminiques */
.carences-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr)); gap: 12px; }
.carence-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--danger); border-radius: 3px;
  padding: 12px 14px;
}
.carence-card h5 { font-family: var(--font-serif); font-weight: 500; font-size: 14.5px; margin: 0 0 6px; color: var(--danger); }

/* =========================================================
   4 piliers + tableau JP Bouchon (onglet 07)
   ========================================================= */
.bouchon-tab tbody th { width: 0; }
.bouchon-tab td       { vertical-align: top; width: 50%; }
.bouchon-tab thead th { font-size: 11px; }

.piliers-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-radius: 4px; padding: 16px 20px; margin: 16px 0;
}
.piliers-head h3 { font-family: var(--font-serif); font-weight: 500; font-size: 19px; margin: 0; color: var(--spe-neuro); }
.piliers-sub     { font-family: var(--font-mono); font-size: 10.5px; letter-spacing: .12em; text-transform: uppercase; color: var(--ink-3); margin: 4px 0 12px; }
.piliers-grid {
  display: grid; grid-template-columns: repeat(auto-fit, minmax(150px, 1fr)); gap: 12px;
}
.pilier {
  background: var(--paper-2); border: 1px solid var(--rule);
  border-top: 3px solid var(--spe-neuro); border-radius: 3px;
  padding: 12px 14px; text-align: center;
}
.pilier .pilier-icon { font-size: 28px; line-height: 1; display: block; margin-bottom: 6px; }
.pilier h5 { font-family: var(--font-serif); font-weight: 500; font-size: 14.5px; margin: 0 0 5px; color: var(--spe-neuro); }
.pilier p  { margin: 0; font-size: 11.5px; color: var(--ink-2); line-height: 1.45; }

/* =========================================================
   Alzheimer (onglet 08) — frise + cards
   ========================================================= */
.alzheimer-frise { margin-bottom: 18px; background: var(--paper); border: 1px solid var(--rule); border-radius: 4px; padding: 18px 20px; }
.alzheimer-frise .frise-axis  { stroke: var(--ink-3); stroke-width: 1; }
.alzheimer-frise .frise-phase { stroke: var(--ink-3); stroke-width: 1; }
.alzheimer-frise .frise-phase.phase-1 { fill: color-mix(in oklab, var(--ok)   18%, var(--paper-2)); }
.alzheimer-frise .frise-phase.phase-2 { fill: color-mix(in oklab, var(--warn) 18%, var(--paper-2)); }
.alzheimer-frise .frise-phase.phase-3 { fill: color-mix(in oklab, var(--danger) 18%, var(--paper-2)); }
.alzheimer-frise .frise-phase-title { font-family: var(--font-serif); font-size: 13px; fill: var(--ink); font-weight: 500; }
.alzheimer-frise .frise-phase-sub   { font-family: var(--font-mono); font-size: 10px; fill: var(--ink-3); letter-spacing: .04em; }
.alzheimer-frise .frise-time { font-family: var(--font-mono); font-size: 9.5px; fill: var(--ink-3); }
.alzheimer-frise .frise-anno { font-family: var(--font-mono); font-size: 10px; fill: var(--ink-3); letter-spacing: .04em; }

.alzheimer-phases { display: grid; grid-template-columns: repeat(auto-fit, minmax(280px, 1fr)); gap: 14px; margin-bottom: 18px; }
.phase-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--spe-neuro); border-radius: 3px;
  padding: 14px 16px;
}
.phase-card .phase-head { display: flex; align-items: baseline; gap: 10px; margin-bottom: 8px; flex-wrap: wrap; }
.phase-card .phase-n    { font-family: var(--font-mono); font-size: 10px; letter-spacing: .12em; text-transform: uppercase; color: var(--spe-neuro); }
.phase-card h4          { font-family: var(--font-serif); font-weight: 500; font-size: 15.5px; margin: 0; color: var(--ink); }
.phase-card .phase-duree{ font-family: var(--font-mono); font-size: 10px; color: var(--ink-3); border: 1px solid var(--rule); padding: 2px 6px; border-radius: 2px; }
.phase-card p           { margin: 0 0 10px; font-size: 12.5px; color: var(--ink-2); line-height: 1.55; }
.phase-card .phase-meta { display: flex; gap: 10px; flex-wrap: wrap; }
.phase-card .phase-mmse,
.phase-card .phase-bio  { font-family: var(--font-mono); font-size: 10px; letter-spacing: .04em; color: var(--ink-3); padding: 3px 7px; border-radius: 2px; background: var(--bg-2); }

.alzheimer-dd-card .dd-head { border-bottom-color: var(--rule); }
.alzheimer-dd-card h4 { color: var(--spe-neuro); }

.ma-pec-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(250px, 1fr)); gap: 12px; margin-bottom: 16px; }
.ma-pec-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-top: 3px solid var(--ok); border-radius: 3px;
  padding: 12px 14px;
}
.ma-pec-card h5 { font-family: var(--font-serif); font-weight: 500; font-size: 14.5px; margin: 0 0 5px; color: var(--ok); }
.ma-pec-card p  { margin: 0; font-size: 12.5px; color: var(--ink-2); line-height: 1.5; }

/* =========================================================
   Tableau bilan bio (onglet 09)
   ========================================================= */
.bio-tab tr.row-highlight { background: color-mix(in oklab, var(--warn) 8%, var(--paper)); }
.bio-tab tr.row-highlight th { color: var(--warn); }

.exam-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--spe-cardio); border-radius: 3px;
  padding: 14px 18px; margin-bottom: 12px;
}
.exam-card h4 { font-family: var(--font-serif); font-weight: 500; font-size: 17px; margin: 0 0 10px; color: var(--spe-cardio); }
.exam-block   { margin: 10px 0; padding-top: 8px; border-top: 1px dashed var(--rule); }
.exam-block:first-of-type { border-top: none; padding-top: 0; }
.exam-tag {
  display: inline-block; font-family: var(--font-mono); font-size: 9.5px;
  letter-spacing: .12em; text-transform: uppercase; color: var(--spe-cardio);
  padding: 2px 7px; border: 1px solid var(--spe-cardio); border-radius: 2px;
  background: var(--paper-2); margin-bottom: 6px;
}
.exam-block ul { margin: 4px 0 0; padding-left: 18px; font-size: 12.5px; color: var(--ink-2); }
.exam-block ul li { margin: 4px 0; line-height: 1.5; }
.exam-block p  { margin: 4px 0 0; font-size: 12.5px; color: var(--ink-2); line-height: 1.5; }

/* Schéma algo */
.algo-box { fill: var(--paper-2); stroke: var(--spe-cardio); stroke-width: 1.2; }
.algo-box.algo-cond { stroke-dasharray: 4 3; }
.algo-title { font-family: var(--font-serif); font-size: 12.5px; fill: var(--ink); }
.algo-sub   { font-family: var(--font-mono); font-size: 10px; fill: var(--ink-3); letter-spacing: .04em; }
.algo-arrow { stroke: var(--spe-cardio); stroke-width: 1.5; fill: none; }

/* =========================================================
   Schémas (onglet 04 + 10)
   ========================================================= */
.schema-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--spe-neuro); border-radius: 4px;
  padding: 16px 20px; margin: 14px 0;
}
.schema-card .schema-cap {
  font-family: var(--font-mono); font-size: 10.5px; letter-spacing: .12em; text-transform: uppercase;
  color: var(--spe-neuro); margin-bottom: 10px; font-weight: 500;
}
.schema-card .schema-svg { width: 100%; height: auto; max-height: 320px; }
.schema-foot { margin: 8px 0 0; font-size: 11.5px; color: var(--ink-3); font-style: italic; text-align: center; }

.schema-axis        { stroke: var(--ink-3); stroke-width: 1.5; }
.schema-axis-label  { font-family: var(--font-mono); font-size: 10.5px; fill: var(--ink-3); letter-spacing: .04em; }
.reserve-curve      { fill: none; stroke: var(--spe-neuro); stroke-width: 3; stroke-linecap: round; }
.reserve-dot        { fill: var(--spe-neuro); stroke: #fff; stroke-width: 1.5; }
.reserve-anno       { font-family: var(--font-mono); font-size: 10px; fill: var(--ink-2); letter-spacing: .04em; }
.reserve-anno-end   { text-anchor: end; }

/* Neurotransmission */
.nt-box        { fill: var(--paper-2); stroke-width: 1.4; }
.nt-box.nt-ach  { stroke: var(--danger); }
.nt-box.nt-dopa { stroke: var(--ok); }
.nt-box.nt-sero { stroke: var(--spe-cardio); }
.nt-box.nt-cort { stroke: var(--warn); }
.nt-box.nt-cyto { stroke: var(--spe-infectio); fill: color-mix(in oklab, var(--spe-infectio) 8%, var(--paper-2)); }
.nt-title  { font-family: var(--font-serif); font-size: 12.5px; fill: var(--ink); font-weight: 500; }
.nt-sub    { font-family: var(--font-mono); font-size: 10px; fill: var(--ink-3); letter-spacing: .04em; }
.nt-arrow  { stroke: var(--ink-3); stroke-width: 1; fill: none; stroke-dasharray: 3 2; }
.nt-arrow-strong { stroke: var(--danger); stroke-width: 2; fill: none; }
.nt-result { fill: var(--danger); stroke: var(--danger); }
.nt-result-text { fill: var(--paper); font-family: var(--font-serif); font-size: 13px; font-weight: 500; }

/* TDM HSD (3 stades) */
.radio-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-radius: 4px; padding: 18px 22px; margin: 16px 0;
}
.radio-card h3 {
  font-family: var(--font-serif); font-weight: 500; font-size: 20px; margin: 0 0 12px; color: var(--spe-neuro);
}
.radio-card ul { padding-left: 20px; margin: 0 0 16px; font-size: 13px; color: var(--ink-2); }
.radio-card ul li { margin: 5px 0; line-height: 1.55; }

.hsd-stades { display: grid; grid-template-columns: repeat(3, 1fr); gap: 14px; margin-top: 12px; }
.hsd-stade  {
  background: var(--paper-2); border: 1px solid var(--rule);
  border-radius: 3px; padding: 12px; text-align: center;
}
.hsd-stade-cap { font-family: var(--font-serif); font-size: 14px; color: var(--ink); margin-bottom: 4px; }
.hsd-stade-delai { font-family: var(--font-mono); font-size: 10px; color: var(--ink-3); margin-left: 6px; }
.hsd-stade-densite { font-size: 11.5px; color: var(--ink-2); margin-top: 6px; }
.hsd-svg { width: 100%; max-width: 180px; height: auto; margin: 0 auto; display: block; }
.hsd-skull  { fill: #f0e8d3; stroke: var(--ink-3); stroke-width: 1.5; }
.hsd-brain  { stroke: var(--ink-3); stroke-width: 1; }
.hsd-ventr  { fill: #1a1713; stroke: none; }
.hsd-ventr.ventr-dilat { fill: #1a1713; stroke: #f3dccf; stroke-width: 1; }
.hsd-shift  { stroke: var(--danger); stroke-width: 2; fill: none; }

/* HCA */
.hca-grid { display: grid; grid-template-columns: 1.2fr 1fr; gap: 18px; align-items: center; }
.hca-text ul { padding-left: 20px; margin: 0; font-size: 13px; color: var(--ink-2); }
.hca-img svg { width: 100%; max-width: 320px; display: block; margin: 0 auto; }
.evans-line   { stroke: var(--danger); stroke-width: 1.5; }
.evans-line-2 { stroke: var(--ok); stroke-width: 2; }
.evans-tick   { stroke: var(--danger); stroke-width: 1.5; }
.evans-label  { font-family: var(--font-mono); font-size: 10px; fill: var(--danger); letter-spacing: .04em; }
.schema-cap-foot { font-family: var(--font-sans); font-size: 11px; fill: var(--ink-3); font-style: italic; }
.schema-cap-sub  { font-family: var(--font-mono); font-size: 10px; fill: var(--ink-3); letter-spacing: .04em; }

/* TEP / TEMP */
.nuc-grid { display: grid; grid-template-columns: 1.2fr 1fr; gap: 18px; align-items: center; }
.nuc-text ul { padding-left: 20px; margin: 0; font-size: 13px; color: var(--ink-2); }
.nuc-img svg { width: 100%; max-width: 320px; display: block; margin: 0 auto; }

/* Pédiatrie */
.ped-etio-tab tbody th { width: 18%; }

/* =========================================================
   PEC pharmaco (onglet 13)
   ========================================================= */
.pec-non-medic-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(240px, 1fr)); gap: 12px; margin-bottom: 16px; }
.pec-card {
  background: var(--paper); border: 1px solid var(--rule);
  border-left: 3px solid var(--ok); border-radius: 3px;
  padding: 12px 14px;
}
.pec-card h5 { font-family: var(--font-serif); font-weight: 500; font-size: 14.5px; margin: 0 0 5px; color: var(--ok); }
.pec-card p  { margin: 0; font-size: 12.5px; color: var(--ink-2); line-height: 1.5; }

.pharma-tab tbody th { width: 18%; }
.pharma-tab .pharma-flag { width: 32px; text-align: center; font-size: 16px; padding: 11px 4px; border-right: 1px solid var(--rule); }
.pharma-tab .pharma-classe {
  display: block; margin-top: 2px;
  font-family: var(--font-mono); font-size: 9.5px; letter-spacing: .08em; text-transform: uppercase; color: var(--ink-3);
}
.pharma-tab tr.pharma-row-warn { background: color-mix(in oklab, var(--warn)   6%, transparent); }
.pharma-tab tr.pharma-row-ok   { background: color-mix(in oklab, var(--ok)    10%, transparent); }
.pharma-tab tr.pharma-row-warn .pharma-flag { color: var(--warn); }
.pharma-tab tr.pharma-row-ok   .pharma-flag { color: var(--ok); }

/* =========================================================
   DARK MODE (body.dark-mode)
   ========================================================= */
body.dark-mode .hsd-skull { fill: #2a2520; stroke: #d7ccb4; }
body.dark-mode .hsd-brain { stroke: #d7ccb4; }
body.dark-mode .hsd-ventr { fill: #0a0807; }
body.dark-mode .hsd-ventr.ventr-dilat { fill: #0a0807; stroke: #f3dccf; }
body.dark-mode .schema-card .nt-box        { fill: #1f1c18; }
body.dark-mode .schema-card .nt-box.nt-cyto { fill: color-mix(in oklab, var(--spe-infectio) 14%, #1f1c18); }
body.dark-mode .schema-card .algo-box      { fill: #1f1c18; }
body.dark-mode .conf-dem-tab .cell-conf    { background: color-mix(in oklab, var(--warn)      18%, transparent); }
body.dark-mode .conf-dem-tab .cell-dem     { background: color-mix(in oklab, var(--spe-neuro) 18%, transparent); }
body.dark-mode .mmwrap svg.canvas {
  background-image: radial-gradient(circle at 1px 1px, rgba(255, 255, 255, .04) 1px, transparent 0);
}
body.dark-mode .mmwrap svg.canvas .node-bg { fill: #1a1713; stroke: #888070; }
body.dark-mode .pilier { background: #1f1c18; }

/* =========================================================
   Responsive
   ========================================================= */
@media (max-width: 900px) {
  .kp-grid, .def-grid { grid-template-columns: 1fr; }
  .hsd-stades { grid-template-columns: 1fr; }
  .hca-grid, .nuc-grid { grid-template-columns: 1fr; }
  .piliers-grid { grid-template-columns: repeat(2, 1fr); }
  .conf-dem-tab tbody th { width: 30%; }
}